LNME.AO

Gentamicina

Prescription Hospital MunicipalHospital Geral e/ou Especializado

Overview

National code
28-16001RP
UNSPSC
51281651
Composition
40 mg/2ml (sulfato) e 80mg/2ml
Presentation
solução injectável
Prescription
Required
Levels of care
Hospital Municipal, Hospital Geral e/ou Especializado
ATC code
J01GB03

Dose calculator

Estimate from the rules recorded for this medicine. Always confirm before prescribing.

⚠️ The calculator is an aid: always confirm the dose against your local clinical protocol. Rules marked “pending review” have not yet been validated by a pharmacist or doctor.

Safety and references

  • The result is a calculation aid, not a prescription: check it against the leaflet, the local protocol or a pharmacist.
  • Obese patients: a per-kg dose may call for ideal or adjusted weight, not actual weight.
  • Renal or hepatic impairment may require adjusting the dose or the interval.
  • Chemotherapy and other narrow-margin drugs only with a specialist.
  • Check the units (mg or mcg, IU, ml) and that the weight is plausible before giving the drug.

References

  1. Bates DW, et al. Incidence of adverse drug events and potential adverse drug events. JAMA. 1995;274(1):29-34.
  2. Merry AF, Anderson BJ. Medication errors — new approaches to prevention. Paediatr Anaesth. 2011;21(7):743-753.

Interactions

  • Grave Tenofovir

    Clinical effect: Aumenta o risco de lesão renal.

    Recommendation: Evitar ou monitorizar a creatinina de forma frequente.

    Source: OMS: diretrizes de VIH

  • Grave Anfotericina b

    Clinical effect: Aumenta o risco de lesão renal.

    Recommendation: Evitar ou vigiar a função renal de perto.

    Source: BNF

  • Grave Amikacina

    Clinical effect: Aumenta o risco de lesão renal, perda de audição e bloqueio neuromuscular.

    Recommendation: Não associar dois aminoglicosídeos.

    Source: BNF

  • Grave Vancomicina

    Clinical effect: Nefrotoxicidade e ototoxicidade aditivas.

    Recommendation: Monitorizar creatinina, ureia, audição e dosagens séricas de ambos.

    Source: BNF / Goodman & Gilman

  • Grave Ciclosporina

    Clinical effect: Nefrotoxicidade aditiva.

    Recommendation: Monitorizar creatinina e ureia. Dosar aminoglicosídeo. Evitar combinação se possível.

    Source: BNF / Transplant Guidelines

  • Grave Furosemida

    Clinical effect: Furosemida potencia a nefrotoxicidade e ototoxicidade dos aminoglicosídeos.

    Recommendation: Monitorizar função renal, eletrólitos e audiometria. Evitar uso simultâneo se possível.

    Source: BNF / Goodman & Gilman

  • Moderada Ibuprofeno

    Clinical effect: Os anti-inflamatórios não esteroides podem aumentar as concentrações de gentamicina e o risco de lesão renal.

    Recommendation: Monitorizar a função renal e as concentrações de gentamicina.

    Source: BNF

  • Moderada Suxametónio

    Clinical effect: Os aminoglicosídeos prolongam o bloqueio neuromuscular.

    Recommendation: Vigiar a recuperação respiratória no pós-operatório.

    Source: BNF

⚠️ The drug-interaction analysis in LNME.AO is for information only and does not replace clinical or pharmaceutical validation by a professional.

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